Theranostic Targets
GP88: A&G cofounder Ginette Serrero, PhD, discovered a biomarker for breast cancer with far-reaching therapeutic and diagnostic capabilities termed “PC Cell-Derived Growth Factor ” (PCDGF|GP88, or GP88). GP88 is an 88 kDa Glycoprotein autocrine growth factor (thus named GP88) that is produced by cancer cells and, in turn, binds back to the same cancer cells, fueling the growth of the breast cancer. GP88 thus plays a major role in promoting human metastatic breast cancer cell survival, growth, and invasiveness. A&G is developing both therapeutic and diagnostic products with this new theranostic target.